Avera Research Institute

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The world of research is dynamic, an ever-changing environment where robust therapies are discovered and tested, and one day put into practice. Avera Research Institute plays a vital role in national clinical trials, participating in several for pediatrics and community and faculty-initiated studies.

That’s where Avera Research Institute comes in. We build upon Avera’s strong commitment to population health, particularly American Indian health, and the integration of clinical research studies within the health system.

To conduct our research, we have offices in Sioux Falls, Rapid City and Pine Ridge, SD, where our researchers engage in partnerships with American Indian communities, community-based organizations and clinics/hospitals.

IDeA States Pediatric Clinical Trials Network

In 2020, Avera Research Institute joined the ECHO IDeA States Pediatric Clinical Trials Network (ISPCTN) as a new opportunity to bring clinical trials to IDeA eligible states/territories identified by the National Institutes of Health (NIH). The ECHO program established ISPCTN to ensure access to clinical trials for states that have historically low NIH funding. In addition to the overall ECHO goal, the focus of the Network includes:

  • Providing access to state-of-the-art clinical trials to medically underserved and rural population in the five ECHO key pediatric outcomes that have a high public health impact.
  • Building national pediatric research capacity to conduct clinical trials by providing team support, infrastructure building, and professional development for faculty including early state investigators.

Experts in Community Research

Child Health Research

Avera is one of only 35 nationwide cohorts chosen to participate in Environmental Influences on Child Health Outcomes, (ECHO) – a national research program launched and supported by the National Institutes of Health. The goal of this study is to improve child and adolescent health by looking at how a broad range of environmental influences – including sleep, nutrition, allergens and social relationships – affect children both prenatally and after birth.

ECHO builds upon research completed during the Safe Passage study, a project that investigated the association between prenatal alcohol exposures, SIDS, and stillbirth. The ECHO study is also enrolling women who are currently pregnant and planning to deliver at any hospital within the Avera Health footprint or a Monument Health facility.

Population Health Research

Our team is dedicated to population health, an approach to health that aims to improve the health of an entire population. Avera Research Institute has focused particularly on the health of American Indian populations. A few studies our team has conducted include:

Questions about Participating in Research?

If you’re interested in participating in a clinical trial at Avera, take time to learn more about clinical research studies and the role of participants. Find out what to expect when you become a research study participant.

Evaluation Services

Avera Research Institute offers evaluation services that are cooperative and culturally sensitive and responsive to the needs of collaborators. Examples of this work include:

  • Developing a proposal for a federal or private grant program
  • Planning and conducting an efficacy study designed to meet evidence-based standards
  • Planning and conducting a cost effectiveness study of a program or policy
  • Working with a health care or school leadership team to plan, roll out, and test new initiatives

Meet Our Researchers

Amy Elliott

Amy Elliott, PhD

Amy Elliott is the Chief Clinical Research Officer at Avera Research Institute and professor at the University of South Dakota School of Medicine. She leads research teams in Sioux Falls, Pine Ridge and Rapid City, SD. Her primary focus is improving child health and development through community-based research. Elliott is the principal investigator on several National Institutes of Health (NIH) research projects including the Environmental Influences on Child Health Outcomes (ECHO) study, examining environmental influences on child health outcomes. She previously worked on the Safe Passage study, an initiative to reduce infant mortality in American Indian communities.

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Kimberlee McKay

Kimberlee McKay, MD

Dr. Kimberlee McKay is the Medical Research Director of Avera Research Institute. She is a board-certified obstetrician gynecologist and provides clinic and hospital services in the Avera McKennan region. She's also the clinical vice president of the Avera OB/GYN service line. McKay has influenced the Avera-OB/GYN services in many ways, including training rural family practice physicians and leads a case collaboration process called TeleEcho that allows regional OB/GYNs to submit difficult cases they’ve encountered to receive feedback from specialized physicians. McKay’s other primary research areas of interest include programs that focus on improving care for rural pregnant women and surrounding tribal communities with significant barriers to OB services and access to care at local facilities.

Jyoti Angal

Jyoti Angal, PhD

Jyoti Angal is the Director of Clinical Research for the Avera Research Institute and instructor at the University of South Dakota School of Medicine. She provides compliance and regulatory expertise on all of the center’s studies, including several National Institutes of Health (NIH) research projects. Angal enjoys managing large research projects and incorporating research ethics in order to improve research design. She’s also passionate about using research to improve maternal and child health in communities with health disparities.

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Arielle Deutsch

Arielle Deutsch, PhD

Arielle Deutsch is a Research Scientist at the Avera Research Institute and an Assistant Professor at the University of South Dakota School of Medicine. Her main areas of interest broadly involve the environments and internal mechanisms of substance use, reproductive and prenatal health, and intimate partner and family violence, focusing on health disparities and inequity for rural, Native, and marginalized communities. She is passionate about collaborating with researchers and non-researchers alike to find practical, effective, and empowering solutions to improve health equity and overall health for those in need.

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Christine Hockett

Christine Hockett, PhD

Christine Wey Hockett is the Director of Community Research at Avera Research Institute in Rapid City, SD, and Assistant Professor at the University of South Dakota School of Medicine. Her research uses observational and community-based intervention methodology to understand how prenatal exposures and behaviors influence infant and childhood health outcomes, specifically in the areas of obesity, diabetes, and child development. Her ultimate goal is to reduce health disparities among rural and American Indian populations.

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Lacey McCormack

Lacey A. McCormack, PhD, MPH, RD

Lacey Arneson McCormack is a Research Scientist at Avera Research Institute and an Associate Professor at the University of South Dakota School of Medicine. Her research focuses on how the rural environment shapes the diet and physical activity behaviors of individuals across the lifespan and contributes to rural health disparities. Additionally, she provides evaluation expertise to several transdisciplinary projects throughout the health system largely focused on rural health and healthcare delivery.

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Clinical Trial Categories

1 Trial Community Health
8 Trials COVID-19
5 Trials Adult
3 Trials Pediatric
2 Trials Infectious Disease
1 Trial Observational Studies
1 Trial Parkinson’s
7 Trials Pediatrics
1 Trial Pulmonology

Research Institute Locations