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Avera on Louise Health Campus

Avera on Louise Health Campus

6100 S Louise Ave, Sioux Falls, SD 57108

Sunday 24 Hours
Monday 24 Hours
Tuesday 24 Hours
Wednesday 24 Hours
Thursday 24 Hours
Friday 24 Hours
Saturday 24 Hours

Hours vary by clinic. See individual locations for details.

Finding Us: Our campus is along South Louise Avenue and extends between 69th and 77th streets. We are conveniently located south of the Interstate 229 and Louise Avenue exit – and near many hotels and retail locations. Free parking is available throughout campus.

Located Inside

digestive disease building update rendering.

New Digestive Health Building

As Sioux Falls grows, Avera will expand to care for patients now and in the future. We’ll build a new, dedicated digestive health building on the Avera on Louise Health Campus. Gastroenterology services currently in the Avera Specialty Hospital will move there in early 2026, also opening more space for growing orthopedic services.

Learn More

Locations Inside

Nearby Locations